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An Impact of Suspected Peritubal Adhesions by Hysterosalpingography on Outcomes of Intrauterine Insemination

An Impact of Suspected Peritubal Adhesions by Hysterosalpingography on Outcomes of Intrauterine Insemination

作     者:Dan-dan WU Zhi-hong NIU Ai-jun ZHANG Rui-huan GU Yun FENG Dan-dan WU;Zhi-hong NIU;Ai-jun ZHANG;Rui-huan GU;Yun FENG;Center of Reproductive Medicine,Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

作者机构:Center of Reproductive MedicineRuijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine 

出 版 物:《Journal of Reproduction and Contraception》 (生殖与避孕(英文版))

年 卷 期:2013年第24卷第3期

页      面:173-180页

学科分类:1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

基  金:funded by Special Foundation for Outstanding Young Teachers in Higher Education Institutions of Shanghai(2012) 

主  题:hysterosalpingography peritubal adhesion ovulation induction intrauterine insemination 

摘      要:Objective To assess the fertility prospect of women with suspected peritubal adhesions diagnosed by hysterosalpingography (HSG) treated with intrauterine insemination (IUI). Methods The study group consisted of 93 patients diagnosed as bilateral suspected peritubal adhesions by HSG, and 175 patients with no tubal pathology were classified as control group. A total of 496 cycles of lUI were finished in 268 infertile women. Results There were no differences in basic clinical parameters between the two groups. Cumulative pregnancy rates after two cycles of lUI were 19.4%for the study group, and 34.3%for the control. Cumulative pregnancy rate in the women with abnormal contrast media loculation was significantly lower than that in women of the control (7.4% vs 34.3%, P=0.037). The cumulative pregnancy rates were similar between the women with abnormal tubal contour and the normal ones (36. 7% vs 34.3%, P=0.800). Conclusion Suspected peritubal adhesions in HSG were worthy more attention, since the outcome of lUI in women with loculation of contrast material, combined with or without abnormal tubal contour resulted in a significantly lower pregnancy rate than the normal ones. IUI should be delayed before tubal patency was confirmed during these patients.

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