Organocatalytic asymmetric allylic alkylation of sulfonylimidates with Morita-Baylis-Hillman carbonates

作     者：PENG Jing,CUI HaiLei & CHEN YingChun Key Laboratory of Drug-Targeting and Drug Delivery System,Ministry of Education Department of Medicinal Chemistry,West China School of Pharmacy,Sichuan University,Chengdu 610041,China 

作者机构：1. Key Laboratory of Drug-Targeting and Drug Delivery System Ministry of Education Department of Medicinal Chemistry West China School of Pharmacy Sichuan University Chengdu 610041 China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2011年第54卷第1期

页      面：81-86页

核心收录：

学科分类：081705[工学-工业催化] 08[工学] 0817[工学-化学工程与技术] 

基　　金：financially Supported by the National Natural Science Foundation of China (20772084) 

主　　题：organocatalysis asymmetric allylic alkylation sulfonylimidates Morita-Baylis-Hillman carbonates cinchona alkaloids 

摘      要：The asymmetric allylic alkylation reaction of sulfonylimidates with various Morita-Baylis-Hillman (MBH) carbonates was accomplished by the catalysis of commercially available cinchona alkaloids catalyst (DHQD)*** corresponding allylic alkylation products were obtained in good yields with high stereoselectivities (up to 99% ee,89:11 dr).