Study on Interaction of L-Tryptophan with p-Suffonatocalix[4]arene by Spectrofluorometry

作     者：Wen Ye LI Ying Li WEI Wen Ting AN Shao Min SHUANG Man Shing WONG 

作者机构：School of Chemistry and Chelmcal Engmeenng Shanxi University Taiyuan 030006 Department of Chemistry Hong Kong Baptist University Hong Kong 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2006年第17卷第12期

页      面：1592-1594页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China(No.20575038) 

主　　题：L-Tryptophan p-sulfonatocalixarene fluorescence. 

摘      要：The interactions between L-tryptophan（L-Trp） and water-soluble p-sulfonatocalix[4]- arene （SCX4） were investigated by spectrofluorometry. The effect of pH was discussed. The interaction process was estimated from the thermodynamic viewpoint. The SCX4 was found to be able to adjust its conformation to fit the size of L-Trp, and the benzene of L-Trp penetrated into the hydrophobic cavity of SCX4. Meanwhile, the binding mechanism was further elucidated by IHNMR and molecular mechanics calculations.