Synthesis of (s)-(-)-Benzyl-2-tert-butoxycarbonyl amino-4-iodobutyrate

作     者：Xin Rong QIN Quan LI Yu Yuan XIE 

作者机构：State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaShanghai Institutes for Biological SciencesChinese Academy of ScienceShanghai 200031 

出 版 物：《Chinese Chemical Letters》 (中国化学快报(英文版))

年 卷 期：2001年第12卷第9期

页      面：767-768页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：alpha-amino acid chiral 

摘      要：A convenient method to synthesize (s)-(-)-benzyl-2-tert-butoxy carbonylamino-4-iodobutyrate from L-(+)methionine 1 was reported, the enantiomeric purity of the product was established by comparison of optical rotation data with literature values, indicating that the reaction process occurred without racemization.