Local Pulse Wave Velocity Estimation in the Carotids Using Dynamic MR Sequences

作     者：Mohamad Ayham Darwich Francois Langevin Khaldoun Darwich 

作者机构：Faculty of Technical EngineeringTartus UniversityTartusSyria Advanced Medical Imaging CenterUniversity of Technology of CompiègneCompiègneFrance Faculty of DentistryDamascus UniversityDamascusSyria 

出 版 物：《Journal of Biomedical Science and Engineering》 (生物医学工程（英文）)

年 卷 期：2015年第8卷第4期

页      面：227-236页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Local Pulse Wave Velocity Arterial Elasticity Dynamic Magnetic Resonance Imaging 

摘      要：The current study presents a new protocol for local pulse wave velocity (PWV) measurement using dynamic MR sequences, which have a high temporal resolution (TR 6 ms). MR images were obtained at two positions along the common carotid artery, separated by a distance of 5 cm. In each phase of a MR series, carotid region was automatically extracted and then its area distension waveform could be obtained. Sixteen volunteers with no symptoms of cardiovascular diseases were studied. For local PWV estimation, three delay estimation principles were tested and produced the following values: intersecting tangents method (M1): 4.72 ± 1.40 m/s, second derivative method (M2): 4.94 ± 1.68 m/s and cross-correlation method (M3): 5.03 ± 1.17 m/s. The cross-correlation method showed a relative high reliability as its least standard deviation.