Assessment of Iron Profile among Transfused Dependent Chronic Renal Failure Sudanese Patients

作     者：Moram Bder Aldein Abd Alla Khalid Mohamed Adam Nasr Eldeen Ali Mohammed Moram Bder Aldein Abd Alla;Khalid Mohamed Adam;Nasr Eldeen Ali Mohammed

作者机构：Department of Hematology Faculty of Medical Laboratory Sciences Al-Neelain University Khartoum Sudan Faculty of Applied Medical Sciences Bisha University Bisha KSA 

出 版 物：《Journal of Biosciences and Medicines》 (生物科学与医学（英文）)

年 卷 期：2016年第4卷第8期

页      面：52-56页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Iron Profile Serum Iron Serum Ferritin Total Iron Binding Capacity CKD 

摘      要：Background: Anemia is one of the complications of chronic kidney disease (CKD) which necessitates multiple blood transfusions. These multiple transfusions are usually accompanied by Iron over load. The current study aimed to assess the Iron profile in Sudanese patients with chronic renal failure received regular blood transfused. Materials and Methods: A descriptive analytical case control study was performed in Alturki Teaching Hospital, Khartoum, Sudan. A total of 90 Sudanese were enrolled in this study (30 CKD patients under hemodialysis and undergo multiple blood transfusion, 30 CKD patients under hemodialysis but not blood transfusion and 30 healthy controls, 51 (57%) were male and 39 (43%) were females, their age ranged between 28 to 75 years. Iron profile (serum iron, serum ferritin and total iron binding capacity (TIBC)) were measured using full automated Chemical analyzer Mindray BS 200 (China). Data were analyzed by using statistical package for social sciences (SPSS) verssion16. Results: The present study showed that serum iron and serum ferritin of those under hemodialysis and received regular blood transfusion patient were significantly higher compared to those under hemodialysis and did not received regular blood transfusion patients (P value 0.000 and 0.01) respectively. Conclusion: Patients with chronic renal failure and under hemodialysis and receive regular and multiple transfusions are prone to iron overload.