End Stage Renal Disease in a Child with Epidermolysis Bullosa

作     者：Felipe Cavagnaro María Joao Yubero Marcela Valenzuela Francis Palisson Felipe Cavagnaro;María Joao Yubero;Marcela Valenzuela;Francis Palisson

作者机构：Facultad de Medicina Clínica Alemana-Universidad del Desarrollo Santiago Chile Clínica Alemana de Santiago Santiago Chile Fundación DEBRA-Chile Santiago Chile Unidad de Nefrología Pediátrica Hospital Guillermo Grant Benavente Concepción Chile 

出 版 物：《International Journal of Clinical Medicine》 (临床医学国际期刊（英文）)

年 卷 期：2016年第7卷第7期

页      面：433-436页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Epidermolysis Bullosa Tubulointerstitial Nephritis Chronic Renal Failure Dialysis 

摘      要：Epidermolysis bullosa (EB) is an inherited connective tissue disease causing blisters in the skin and mucosal membranes. In severe cases, EB may be associated with renal damage through several mechanisms, mainly immunological ones. The present case described a young male with dystrophic recessive EB who developed an advanced chronic renal damage secondary to tubulointerstitial nephritis that was demonstrated by a renal biopsy. Unpublished previously, this complication should be considered among the possible causes of renal damage in EB. Also it is recommended a protocoled surveillance of renal and urinary tract complications in children with EB.