Two Cases of Tuberculosis Manifesting as Cutaneous Solitary Mass in Patients with Adult T-Cell Leukemia/Lymphoma
Two Cases of Tuberculosis Manifesting as Cutaneous Solitary Mass in Patients with Adult T-Cell Leukemia/Lymphoma作者机构:Department of Dermatology Faculty of Medicine Fukuoka University Fukuoka Japan Department of Respiratory Medicine Fukuoka University School of Medicine Fukuoka Japan
出 版 物:《Journal of Tuberculosis Research》 (结核病研究(英文))
年 卷 期:2016年第4卷第3期
页 面:134-139页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:Tuberculosis Tuberculous Lymphadenitis Immunosuppression Adult T-Cell Leukemia/Lymphoma Regulatory T-Cell
摘 要:Tuberculosis (TB) is a major public health problem worldwide and a large number of fatal cases are still reported. Immunocompetent individuals are naturally susceptible to TB, and immunocompromised patients have a greater risk of infection. Although patients with adult T-cell leukemia/lymphoma (ATL) are in an immunosuppressed condition, there is only one reported case of TB accompanied with ATL in the English- language literature in the field of dermatology. Here, we report two patients with chronic-type ATL infected with TB manifesting as cutaneous solitary masses. Case 1 was a 58-year-old woman diagnosed with lumbar abscess with pulmonary TB. Case 2 was an 84-year-old woman diagnosed with tuberculous lymphadenitis in the left cervical region. It is important to raise the differential diagnosis of TB and perform tissue culture for acid-fast bacilli as well as Interferon-Gamma release assay test when dermatologists encounter mass lesions in patients with ATL.