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Primary Thyroid Non-Hodgkin’s Lymphoma

Primary Thyroid Non-Hodgkin’s Lymphoma

作     者:Madiha Mahfoudhi Khaled Khammassi Imen Gorsane Mounira El Euch Sami Turki Mamia Ben Salah Taieb Ben Abdallah 

作者机构:Department of Internal Medicine Charles Nicolle Hospital Tunis Tunisia Department of Oto-Rhino-Laryngology Charles Nicolle Hospital Tunis Tunisia 

出 版 物:《Open Journal of Pathology》 (病理学期刊(英文))

年 卷 期:2015年第5卷第4期

页      面:114-116页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Thyroid Gland Lymphoma Immunohistochemistry 

摘      要:Primary non-Hodgkin’s lymphoma of the thyroid gland was rarely described. We report the case of a 44-year-old man admitted for an anterior neck swelling, hoarseness and dyspnea. The chest radiograph showed a trachea deviation. He had no clinical, biological or radiological sign of other lymphoma locations. Ultrasound examination of the neck revealed a bilateral heterogeneous thyroid lesion. Cytology revealed lymphoid cells having high nuclear-cytoplasmic ratio with multiple and irregular nucleoli. An urgent thyroid surgery consisting of total thyroidectomy had been performed since the presence of compressive signs due to the tumor. The histopathological examination of a biopsy from the thyroid tissue confirmed a high-grade non-Hodgkin’s lymphoma. Then, L-thyroxin substitution therapy, chemotherapy and radiotherapy were initiated. A prolonged remission was noted.

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