In Vitro Evaluation of Polyurethane-Chitosan Scaffolds for Tissue Engineering

作     者：Imelda Olivas-Armendariz Perla Garcia-Casillas Adriana Martel Estrada Alberto Martinez-Villafane Laura A.A.de la Rosa Carlos A.Martinez-Perez 

作者机构：Institute of Engineering and TechnologyAutonnomous University of the City of JuarezCiudad JuarezMexico Department of Physics of MaterialsResearch Center of Advanced MaterialsChihuahuaMexico Institute of Biomedical ScienceAutonomous University of the City of JuarezCiudad JuarezMexico 

出 版 物：《Journal of Biomaterials and Nanobiotechnology》 (生物材料与纳米技术（英文）)

年 卷 期：2012年第3卷第4期

页      面：440-445页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：National Science Council of Mexico CONACyT for their financial support trough the project sep-conacyt 2007-84339 

主　　题：Biomaterials Composite 

摘      要：In this work the use of Polyurethane (PU)-Chitosan(CH) scaffolds prepared by thermal induced phase separation (TIPS) for osteoblast proliferation and bone mineralization is described. Primary rat calvaria osteoblasts were seeded in the scaffolds and it was shown that supported cell adhesion and growth. The behavior osteoblast cells growing in the scaffold in function of the different ratio of PU and CH is presented. The results showed that TIPS is an appropriate technique for the production of PU-CH scaffolds with high potential for application as cell scaffolds in bone tissue engineering.