Vitamin D3: Association of Low Vitamin D3 Levels with Semen Abnormalities in Infertile Males
Vitamin D3: Association of Low Vitamin D3 Levels with Semen Abnormalities in Infertile Males作者机构：Department of Medicine Peoples University of Medical and Health Sciences Nawabshah Pakistan Department of Physiology Peoples University of Medical and Health Sciences for Women Sindh Pakistan Department of Medicine Peoples University of Medical and Health Sciences Nawabshah Pakistan Department of Pediatrics Medicine Peoples University of Medical and Health Sciences for Women Nawabshah Pakistan Department of Urology Peoples University of Medical and Health Sciences for Women Nawabshah Pakistan Department of Cardiology Peoples University of Medical and Health Sciences for Women Nawabshah Pakistan Liaquat University of Medical and Health Sciences Jamshoro Pakistan
出 版 物：《Advances in Sexual Medicine》 (性医学进展（英文）)
年 卷 期：2018年第8卷第4期
页 面：39-59页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Vitamin D Deficiency Sperm Motility Male Infertility
摘 要：Background: Insufficiency of vitamin D is one of the utmost general health issues all over the globe, including Pakistan;incompatible data are present on the possible relationship among serum vitamin D values and quality of semen. Objective: Lack of Vitamin D in body is related with a higher risk of various health problems including infertility. In our setup no such type of study had been conducted in the past on the relationship among serum vitamin D levels and infertility. This study was aimed to investigate male subjects with infertility and serum levels of vitamin D. Methods: This study was cross-sectional and performed on 243 male subjects who attended the clinic for evaluation of infertility from January 2016 to December 2017. Mean age of patients was 31.94 years with standard deviation of 7.52 years. The mean age of controls was 32.2 years with SD 8.42 years, age ranged between 20 years as minimum to 46 years as maximum. The minimum vitamin D level was 7.00 ng/dl while maximum 130 ng/dl, mean was 26.20 and standard deviation was 22.06 ng/ml. Levels of vitamin D were significantly low in (67%) male subjects with infertility. The mean vitamin D level of controls was 49.40 with SD of 35.98 ng/ml. 28% of controls had also vitamin D levels below the normal range, which indicates the prevalence of vitamin D deficiency in general population here in our setup. The participants were divided according to WHO (World Health Organization) 2010 criteria along with corresponding healthy control subjects. A questionnaire for evaluation of infertility in male subjects was filled by all the contestants. Results: Levels of vitamin D were significantly low in (67%) male subjects with infertility. While 28% of controls had also vitamin D levels below the normal range. Infertile male subjects with low or no sperm count were found insufficient for vitamin D in comparison to healthy control subjects. Conclusion: It was concluded from the results of current study that low levels of v
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