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An Efficient and Rapid Synthesis of 2-amino-4-arylthiazoles Employing Microwave Irradiation in Water

An Efficient and Rapid Synthesis of 2-amino-4-arylthiazoles Employing Microwave Irradiation in Water

作     者:Kishor S. Jain Jitender B. Bariwal Muthu K. Kathiravan Vikas K. Raskar Gajanan S. Wankhede Nitin A. Londhe Satish N. Dighe 

作者机构:不详 

出 版 物:《Green and Sustainable Chemistry》 (绿色与可持续化学(英文))

年 卷 期:2011年第1卷第2期

页      面:35-38页

学科分类:07[理学] 0703[理学-化学] 

主  题:Green Chemical Synthesis MWI Water 2-amino-4-arylthiazoles 

摘      要:A facile, high yielding green chemical synthetic protocol adaptable to the parallel synthesis of a library of potentially bioactive 2-amino-4-arylthiazoles is reported herein. The methodology involves the condensation of various aracyl bromides with N-arylthioureas under MWI using water as solvent, to yield pure products (81%-97%) in very short reaction times (1-20 min).

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