An Efficient and Rapid Synthesis of 2-amino-4-arylthiazoles Employing Microwave Irradiation in Water
An Efficient and Rapid Synthesis of 2-amino-4-arylthiazoles Employing Microwave Irradiation in Water作者机构:不详
出 版 物:《Green and Sustainable Chemistry》 (绿色与可持续化学(英文))
年 卷 期:2011年第1卷第2期
页 面:35-38页
主 题:Green Chemical Synthesis MWI Water 2-amino-4-arylthiazoles
摘 要:A facile, high yielding green chemical synthetic protocol adaptable to the parallel synthesis of a library of potentially bioactive 2-amino-4-arylthiazoles is reported herein. The methodology involves the condensation of various aracyl bromides with N-arylthioureas under MWI using water as solvent, to yield pure products (81%-97%) in very short reaction times (1-20 min).