Ultrastructural Characteristics of Sheep and Horse Mesenchymal Stem Cells (MSCs)
Ultrastructural Characteristics of Sheep and Horse Mesenchymal Stem Cells (MSCs)作者机构：Competence Center for Applied Biotechnology and Molecular Medicine (CABMM) Vetsuisse Faculty University of Zurich Zurich Switzerland Department of Histology-Embryology Veterinary Faculty Ankara University Ankara Turkey Department of Surgery Veterinary Faculty Ankara University Ankara Turkey
出 版 物：《Microscopy Research》 (显微镜研究（英文）)
年 卷 期：2013年第1卷第3期
页 面：17-23页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Ultrastructure Mesenchymal Stem Cells (MSCs) TEM Differentiation Equine Ovine
摘 要：In the present study, the morphological and ultrastructural characteristics of mesenchymal stem cells (MSCs) induced towards osteogenic, adipogenic, and chondrogenic lineages were investigated. The main objective of this paper was to focus on the differentiation capacity of ovine [oMSCs] and equine MSCs [eMSCs]. Bone marrow [BM] MSCs were isolated from ovine and equine patients, expanded in monolayer culture and induced into osteogenic, adipogenic and chondrogenic differentiation. For chondrogenic differentiation, cells were cultured in micromass culture. Also, their ultrastructural phenotypes were studied by transmission electron microscopy [TEM]. This study was aimed to provide an indepth morphological description of BM-derived ovine and equine MSCs induced towards three lineages, it demonstrated that TEM analysis is useful in elucidating detailed structural information.
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