Oral manifestations of acute promyelocytic leukemia: A case report

作     者：Daisuke Saito Daisuke Saito Tadaharu Kobayashi Yohei Oda Kanae Niimi Hiroyuki Kano Chikara Saito 

作者机构：Division of Reconstructive Surgery for Oral and Maxillofacial Region Niigata University Graduate School of Medical and Dental Sciences Niigata Japan 

出 版 物：《Open Journal of Stomatology》 (口腔学期刊（英文）)

年 卷 期：2013年第3卷第1期

页      面：25-27页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Acute Promyelocytic Leukemia OralManifestations Oral Care 

摘      要：Acute?leukemia?is?often?associated?with?oral?manifestations.?We?report?an?acute?promyelocytic?leukemia?(APL)?case?with?oral?manifestations?leading?to?the?diagnosis. A?21-year-old?female visited?our?hospital?with?complaints?of?gingival?bleeding?and?swelling?of?the?left?lower?wisdom?tooth.?The?patient’s?complete?blood?count?revealed?a?marked?increase?in?white?blood?cells?and?a?decrease?in?red?blood?cells?and?an?abnormal?leukocyte?differential,?and APL?was?diagnosed?on?the?basis?of?bone?marrow?samples in?the internal?medicine?department.?The?patient?was?treated?with?all-trans-retinoic?acid combined?with?chemotherapy?and?has?maintained?clinical?and?molecular?complete?remission?at?12?months?of?follow-up. Dental?professionals should?be?aware?of?clinical?manifestations?and?complications?associated?with these?malign-nant?neoplastic?diseases?to?aid?in?diagnosis?and?subsequent?treatment?and?management.