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Radiation associated coronary occlusion: Overlooked as trastuzumab-induced cardiomyopathy

Radiation associated coronary occlusion: Overlooked as trastuzumab-induced cardiomyopathy

作     者:Ugur Turk Veysel Yavuz Nurullah Cetin 

作者机构:Department of Cardiology Celal Bayar University Manisa Turkey Department of Cardiology Central Hospital Izmir Turkey 

出 版 物:《Open Journal of Internal Medicine》 (内科学期刊(英文))

年 卷 期:2013年第3卷第1期

页      面:1-2页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Cardiomyopathy Trastuzumab Radiation 

摘      要:Trastuzumab is an agent used for receptor-positive breast cancer. Up to a third of patients treated with trastuzumab might develop cardiomyopathy. Many patients with breast cancer have taken pre- or co-administration of mediastinal radiotherapy. Both of treatment modalities have toxic effects on myocardium. It may result with diagnostic confusion between radiation-induced CAD (riCAD) and trastuzumab cardiomyopathy in the case with dilated cardiomyopathy. TTE may offer clues of differential diagnosis.

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