Radiation associated coronary occlusion: Overlooked as trastuzumab-induced cardiomyopathy
Radiation associated coronary occlusion: Overlooked as trastuzumab-induced cardiomyopathy作者机构:Department of Cardiology Celal Bayar University Manisa Turkey Department of Cardiology Central Hospital Izmir Turkey
出 版 物:《Open Journal of Internal Medicine》 (内科学期刊(英文))
年 卷 期:2013年第3卷第1期
页 面:1-2页
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题:Cardiomyopathy Trastuzumab Radiation
摘 要:Trastuzumab is an agent used for receptor-positive breast cancer. Up to a third of patients treated with trastuzumab might develop cardiomyopathy. Many patients with breast cancer have taken pre- or co-administration of mediastinal radiotherapy. Both of treatment modalities have toxic effects on myocardium. It may result with diagnostic confusion between radiation-induced CAD (riCAD) and trastuzumab cardiomyopathy in the case with dilated cardiomyopathy. TTE may offer clues of differential diagnosis.