Analysis of influencing factors of visual working memory in young adult patients with schizophrenia

作     者：Li Zhang Xuemei Ran Ting Li Yixuan Ku Li Liu Tingming Huang Wenjia Yan Li Zhang;Xuemei Ran;Ting Li;Yixuan Ku;Li Liu;Tingming Huang;Wenjia Yan;Outpatient, Shanghai Changning District Mental Health Center;Institute of Cognitive Neuroscience, East China Normal University

作者机构：Outpatient Shanghai Changning District Mental Health Center Institute of Cognitive Neuroscience East China Normal University 

出 版 物：《General Psychiatry》 (综合精神医学（英文）)

年 卷 期：2018年第31卷第6期

页      面：122-127页

核心收录：

学科分类：10[医学] 

基　　金：Changning District Health and Family Planning Committee Project(20144Y010) 

主　　题：working memory visual The 

摘      要：Background Patients with schizophrenia have general cognitive impairments, and the impairment of working memory is considered to be the basis of cognitive impairments. The research on visual working memory, one of the subcomponents, is getting more and more ***, the influencing factors which cause the deficits of visual working memory in patients with schizophrenia have not been clearly explained. To provide evidence for cognitive impairment interventions, the present study explored the factors influencing the deficits of patients visual working *** The present study discussed the relevant factors influencing the visual working memory of patients with schizophrenia by measuring the accuracy of the visual working memory of patients with schizophrenia and healthy *** Colour-recall paradigm was employed to measure the accuracy of the visual working memory of 61 healthy controls and 61 patients who met the International Classification of Diseases, Tenth Revision diagnostic criteria for schizophrenia. The age range of subjects was18-50. Scale for the Assessment of Positive Symptoms(SAPS) and Scale for the Assessment of Negative Symptoms(SANS) were used to evaluate the patients clinical *** Compared with the healthy control group, the accuracy of visual working memory of patients with schizophrenia was significantly impaired(t=3.062,p=0.003). The accuracy of visual working memory of patients with schizophrenia was not related to age(r=0.023,p=0.860),the age of onset(r=-0.003,p=0.979),the duration of illness(r=-0.038, p=0.769),education level(r=-0.181, p=0.162),continuous working time before illness(r =-0.107, p=0.413) or the daily dose of antipsychotic drugs(r =0.062, p=0.635); however, it was positively related to the number of hospitalisations(r =0.471,p0.001). The total score of Scale for the Assessment of Positive Symptoms(SAPS) was negatively related to the accuracy of visual working memory(r=-0.388, p=0.005), while t