Analysis on the gender-specific risk factors of new-onset cerebral hemorrhage
Analysis on the gender-specific risk factors of new-onset cerebral hemorrhage作者机构:Public Health SchNorth China Sci & Technol Univ
出 版 物:《China Medical Abstracts(Internal Medicine)》 (中国医学文摘(内科学分册(英文版))
年 卷 期:2018年第35卷第4期
页 面:213-213页
学科分类:10[医学]
主 题:the gender-specific risk factors
摘 要:Objective To explore the gender-specific risk factors of new-onset cerebral *** In this prospective cohort study,a total of 98 961 participants((51.1±12.6)years old),who underwent from 2006 to 2007 physical examination and met the inclusion criteria,were enrolled from the Kailuanstudy *** were 78908(79.7%)male,and 20 053(20.3%)*** incidence of cerebral hemorrhage was observed once per year until December 31,*** difference on the incidence of cerebral hemorrhage between male and female was *** Cox regression analysis was applied to analyze the risk factors of cerebral hemorrhage events among different *** The participants were followed up for(10.00±0.73)years,and 860 cerebral hemorrhage events were recorded during follow *** incidence of cerebral hemorrhage in the population was 86.90/10 million person years(standardized incidence rate of 47.85/10 million person years).The incidence of cerebral hemorrhage was significantly higher in male(49.61/10 million person years)than in female(34.07/10 million person years,P0.05).Multivariate Cox regression analysis showed that 45-59 years old,≥60 years old,diabetes,and waist-hipratio were more strongly related to new-onset of cerebral hemorrhage events in female than in male,and the hazard ratios(95% CI)were 2.33(1.23-4.43),2.71(1.30-5.66),2.16(1.24-3.74)and 8.79(1.42-54.32)in female versus 1.55(1.21-1.97),2.16(1.68-2.78),1.19(0.93-1.53)and 3.21(1.09-9.41)in male,*** risk of male cerebral hemorrhage increased by 29%(HR=1.29,95% CI 1.19-1.40)in male and 24%(HR=1.24,95% CI 1.20-1.28)in female,when the systolic blood pressure increased 10 mm Hg(1 mm Hg=0.133 k Pa).Conclusion The incidence of cerebral hemorrhage is higher in male than in female in this *** association between systolic blood pressure and cerebral hemorrhage is stronger in male than that in *** associations between age,waist-hip ratio,diabetes and cerebral hemorrhage are