Effect of the Fu Zheng Method Applied by Hong-Feng CHEN on the Quality of Life in TNBC Patients and Empirical Research Based on Data Mining

作     者：Yu-Zhu ZHANG Yue ZHOU Bai-Ling SHI Hong-Feng CHEN Li-Juan CHE 张玉柱;周悦;时百玲;陈红风;车立娟

作者机构：Shanghai University of Traditional Chinese MedicineShanghai 201203China Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China 

出 版 物：《Digital Chinese Medicine》 (数字中医药（英文）)

年 卷 期：2018年第1卷第4期

页      面：272-279页

学科分类：1006[医学-中西医结合] 1005[医学-中医学] 100502[医学-中医临床基础] 10[医学] 100602[医学-中西医结合临床] 

基　　金：support from the Shanghai TCM Gushi Surgical School Heritage Research Base Construction Project of Shanghai Health Bureau(ZYSNXD-CC-APGC-JD-002) 

主　　题：Triple-negative breast cancer Data mining Traditional Chinese medicine formulas Quality of life Hong-Feng CHEN 

摘      要：Objective To preliminarily evaluate the efficacy of the Fu Zheng method(supporting resistance against pathogenic factors)applied by Professor Hong-Feng CHEN in improving the quality of life in patients with triple-negative breast cancer(TNBC)to collect and organize the traditional Chinese medicine(TCM)formulas applied by Professor Hong-Feng CHEN in the treatment of TNBC in order to explore the patterns in *** The Functional Assessment of Cancer Therapy-Breast scale(FACT-B V4.0)were collected before and after treatment;the database and data mining platform for prescribed TCM formulas were constructed using Microsoft SQL Server 2005,and the patterns in drug pairing and combination were summarized by correlation analysis of data *** The formulas improved the mean scores of the patients’physical well-being,social/family well-being,emotional well-being,physical function well-being and additional concerns(P0.01);the drug combinations and pairs frequently used by Professor Hong-Feng CHEN were *** The TCM formulas applied by Professor Hong-Feng CHEN can alleviate adverse physiological reactions,improve psychological conditions and improve function in *** formulas take spleen invigoration and stomach nourishment as well as blood circulation promotion and stagnation dissipation as the therapeutic principles,with simplicity in prescription and focus on care and protection the foundation of acquired constitution.