Neuromodulation for tinnitus treatment:an overview of invasive and non-invasive techniques

作     者：Nicole PETER Tobias KLEINJUNG Nicole PETER;Tobias KLEINJUNG

作者机构：Department of OtorhinolaryngologyHead and Neck SurgeryUniversity Hospital Zürich 

出 版 物：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 (浙江大学学报（英文版）B辑（生物医学与生物技术）)

年 卷 期：2019年第20卷第2期

页      面：116-130页

核心收录：

学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 0905[农学-畜牧学] 0906[农学-兽医学] 100213[医学-耳鼻咽喉科学] 10[医学] 

主　　题：Tinnitus Neuromodulation Invasive technique Non-invasive technique 

摘      要：Tinnitus is defined as a perception of sound without any external sound *** tinnitus is a frequent condition that can affect the quality of *** far,no causal cure for tinnitus has been documented,and most pharmacologic and psychosomatic treatment modalities aim to diminish tinnitus’impact on the quality of ***,a novel therapeutic modality,which aims at alternating nerve activity through a targeted delivery of a stimulus,has emerged as a potential option in tinnitus *** review provides a brief overview of the current neuromodulation techniques as tinnitus treatment *** main intention is to provide updated knowledge especially for medical professionals counselling tinnitus patients in this emerging field of ***-invasive methods such as repetitive transcranial magnetic stimulation,transcranial electrical stimulation,neurofeedback,and transcutaneous vagus nerve stimulation were included,as well as invasive methods such as implanted vagus nerve stimulation and invasive brain *** of these neuromodulation techniques revealed promising results;nevertheless,further research is needed,especially regarding the pathophysiological principle as to how these neuromodulation techniques work and what neuronal change they *** studies suggest that individually different brain states and networks are involved in the generation and perception of ***,in the future,individually tailored neuromodulation strategies could be a promising approach in tinnitus treatment for achieving a more substantial and longer lasting improvement of complaints.