Olfactory schwannoma:a case report

作     者：Weidong Wu Xiaozhen Zhan Kezhen Wang Chengzhi Cui Kai Xu Peiyu Cong Weidong Wu;Xiaozhen Zhan;Kezhen Wang;Chengzhi Cui;Kai Xu;Peiyu Cong;Department of Neurosurgery, Dalian Municipal Central Hospital;Dalian Medical University

作者机构：Department of NeurosurgeryDalian Municipal Central HospitalDalian 116033China Dalian Medical UniversityDalian 116044China 

出 版 物：《Oncology and Translational Medicine》 (肿瘤学与转化医学（英文版）)

年 卷 期：2018年第4卷第6期

页      面：259-262页

学科分类：10[医学] 

主　　题：olfactory schwannoma anterior skull base schwannoma schwannoma diagnosis treatment 

摘      要：Objective Intracranial schwannomas are frequently located in the VIII cranial nerve, followed by the V and VII cranial nerves, but are quite rare in the olfactory cranial nerves. Here, we report a case of an olfactory schwannoma and review the literature to improve the diagnosis and treatment of olfactory schwannoma. Methods We report a case of olfactory schwannoma in a 51-year-old Chinese man who experienced dizziness and no other *** Magnetic resonance imaging(MRI) showed a neoplastic mass located on the anterior cranial base to the right of the midline and near the cribriform plate and sphenoidal plane. The lesion travelled through the cribriform plate into the nasal cavity. This mass was initially thought to be an olfactory groove meningioma. We performed a craniotomy for surgical excision, and the tumor was completely resected, and the skull base was reconstructed at the same time. There were no complications during surgery, and the patient recovered well. The histopathological diagnosis was a *** Olfactory schwannomas are extremely rare and similar to olfactory ensheating cell tumors, and the immunohistochemical staining of leukocyte antigen 7(Leu7/CD57) can be used to identify them. Although the standard treatment of olfactory schwannoma remains unclear, in all reports, most patients can have excellent prognosis after an effective surgical resection.