Synthesis and Characterization of Ibuprofen-Rectorite Composites by Solution Intercalation Method
Synthesis and Characterization of Ibuprofen-Rectorite Composites by Solution Intercalation Method作者机构:HospitalWuhan University of Teehnology
出 版 物:《Journal of Wuhan University of Technology(Materials Science)》 (武汉理工大学学报(材料科学英文版))
年 卷 期:2009年第24卷第4期
页 面:654-657页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 10[医学]
基 金:Funded by the Program for New Century Excellent Talents in University(NCET05-0662)
主 题:ibuprofen rectorite solution intercalation composites clay
摘 要:The ibuprofen-rectorite composites were prepared by the solution intercalation method using ibuprofen and rectorite as raw materials, and were characterized by X-ray diffraction (XRD) analysis, Fourier transform infrared analysis and scanning electron microscopy (SEM). The experimental results show that the ibuprofen is intercalated into the interlayer spaces of rectorite. The values of the (001) peaks of the ibuprofen-rectorite composite are larger than that of Na-rectorite and reach the largest when the reaction time and ibuprofen amount is 2 h and 0.36 g, respectively. The layered structure of Na-rectorite is destroyed to some extent with the intercalation of ibuprofen into the interlayer space in the structure of Na-rectorite. A part of ibuprofen in the ibuprofen Na-rectorite covers on the surface of Na-rectorite besides some ibuprofen enters into the interlayer space.