The Study of Anti-tumor Activity of Trichosanthin by Cyclic Voltammogram

作     者：Gang XU Cheng Cai AN Jun FENG Yun Xiang CI Jin Hua TIAN Zhang Liang CHENI( National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing 100871College of Chemistry and Molecular Engineeri 

作者机构：National Laboratory of Protein Engineering and Plant Genetic Engineering College of Life Sciences Peking University College of Chemistry and Molecular Engineering Peking University 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2000年第11卷第7期

页      面：597-600页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Doctor's New Medicine Grant of National Science Committee Kyoritsu Women's University, Tokyo,Japan 

主　　题：Trichosanthin (TCS) U937 cells cyclic voltammogram Ribosome Inactivating Proteins (RIPs) 

摘      要：The anti-tumor activity of Trichosanthin (TCS) has been frequently reported in recent years. In our experiments, electrochemical methods were applied to detect the effects of TCS on human leukemia cells U937. 50 mu g/ml TCS treatment for 40 hours can cause irreversible negative effects on the viability of U937 cells. This effect largely depends on the concentration of TCS and the time period of treatment.