Pulmonary Drugs and Genes Delivery Systems for Lung Disease Treatment

作     者：Caina Xu Huayu Tian[*] Xuesi Chen 

作者机构：Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun Jilin 130022 China Email: Huayu Tian (thy@***)[*]Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun Jilin 130022 China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2014年第32卷第1期

页      面：13-21页

核心收录：

学科分类：080901[工学-物理电子学] 0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 080401[工学-精密仪器及机械] 0804[工学-仪器科学与技术] 0803[工学-光学工程] 

基　　金：The authors are thankful to the National Natural Science Foundation of China (Grant Nos.21074129 51222307) Jilin Province Science and Technology Development Program (20120306 20130521011JH) the Open Research Fund of the Key Laboratory of Advanced Technologies of Materials Ministry of Education Southwest Jiaotong University for financial support of this work 

主　　题：pulmonary delivery systems drugs and genes delivery lung disease therapeutic efficacy 

摘      要：Pulmonary drugs and genes delivery systems have become an attractive approach in the treatment of lung diseases with the advantages of minimal drug loss,precise quantization,high local drugs concentration and low side ***,special attention should be paid to the biological barriers of the *** delivery systems need to be designed carefully in order to overcome these biological barriers and maximize the drugs and genes deposition to the *** drugs and genes delivery systems can offer some encouraging results for delivering drugs and genes to the ***,some lipid-based and polymer-based delivery systems could control and sustain the release of drugs and genes with minimal or negligible *** review focuses on the latest development of pulmonary delivery of drugs and genes for the treatment of various lung *** barriers to the lung,the delivery devices,the route of the administration and the delivery systems for drugs and genes pulmonary delivery are *** on the rapid development of clinical requirement,novel approaches using delivery systems for pulmonary delivery drugs and genes need to be constructed,which is believed to play an important role in the therapy of lung diseases in the future.