Medicinal Mushroom Products:Nutriceuticals and/or Pharmaceuticals?

作     者：CHANG Shuting CHANG Shuting

作者机构：Emeritus Professor of Biology The Chinese University of Hong Kong Shatin N. T. Hong Kong SAR China 

出 版 物：《食用菌学报》 (Acta Edulis Fungi)

年 卷 期：2009年第16卷第4期

页      面：80-86页

学科分类：1007[医学-药学(可授医学、理学学位)] 10[医学] 

主　　题：扁圆头铆钉 药物 内科学 医药品 

摘      要：Although the effectiveness of mushroom products(mushroom derivatives) has been confirmed repeatedly by numerous laboratory experiments and,in some cases,human trials,precisely how these products work is still a matter of *** on the effectiveness of mushroom products fall into two general *** approach has been to isolate and determine the bioactivity of individual mushroom components within a particular class of compounds(***,lectins,triterpenoids,fungal immunomodulatory proteins).The active principal component is then sold in refined or purified form,*** polysaccharide lentinan from the edible/medicinal mushroom Lentinula *** an approach is certainly valid if the objective is to focus on a single mushroom-derived substance for the treatment of specific disease conditions,*** or *** such cases,the products might be(and have been) developed and marketed as prescription ***,an alternative approach is not to focus on a single component within a class of compounds but on groups of compounds that improve overall health and the general quality of *** composite formulae,in which several different compounds together contribute to the beneficial effect of the mushroom,could then be used collectively as a dietary supplement(nutriceutical).Thus,the medicinal effects afforded by medicinal mushroom products may be attributable to several quite different types of compounds present in the mushrooms,***,lectins,triterpenoids and fungal immunomodulatory *** compounds,and possibly others yet to be identified,appear to act in concert in contributing to the documented anticancer,antitumour,antiviral,antibacterial and immunomodulating properties of the ***,mushroom nutriceuticals may be deemed to have multifunctional values,the essence of which depends on the integrated effects of the various ***,the overwhelming majority of mushroom-based produc