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Hemobilia: Etiology, diagnosis, and treatment

作     者:Rani Berry James Han Ani A.Kardashian Nicholas F.LaRusso James H.Tabibian Rani Berry;James Han;Ani A.Kardashian;Nicholas F.LaRusso;James H.Tabibian

作者机构:Department of Internal MedicineUCLA Ronald Reagan Medical CenterLos AngelesCAUSA Department of Internal MedicineUniversity of California IrvineIrvineCAUSA UCLA Gastroenterology Fellowship Training ProgramVatche and Tamar ManoukianDivision of Digestive DiseasesLos AngelesCAUSA Division of Gastroenterology and HepatologyMayo ClinicRochesterMNUSA Division of GastroenterologyDepartment of MedicineOlive View-UCLA Medical CenterSylmarCAUSA 

出 版 物:《Liver Research》 (肝脏研究(英文))

年 卷 期:2018年第2卷第4期

页      面:200-208页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基  金:This work was supported by the USA National Institutes of Health grant NIDDK DK057993(to NFL) 

主  题:Hemobilia Upper gastrointestinal hemmorhage Etiology Diagnosis Imaging Hepatopancreatobiliary interventions 

摘      要:Hemobilia refers to bleeding from and/or into the biliary tract and is an uncommon but important cause of gastrointestinal *** of hemobilia date back to the 1600s,but due to its relative rarity and challenges in diagnosis,only in recent decades has hemobilia been more critically *** majority of cases of hemobilia are iatrogenic and caused by invasive procedures involving the liver,pancreas,bile ducts and/or the hepatopancreatobiliary vasculature,with trauma and malignancy rep-resenting the two other leading causes.A classic triad of right upper quadrant pain,jaundice,and overt upper gastrointestinal bleeding has been described(*** s triad),but this is present in only 25%e30%of patients with ***,prompt diagnosis depends critically on having a high index of suspicion,which may be based on a patient s clinical presentation and having recently undergone(peri-)biliary instrumentation or other predisposing *** treatment of hemobilia depends on its severity and suspected source and ranges from supportive care to advanced endoscopic,interventional radiologic,or surgical *** we provide a clinical overview and update regarding the eti-ology,diagnosis,and treatment of hemobilia geared for specialists and subspecialists alike.

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