牛血清蛋白在聚甲基丙烯酸甲酯微球表面的吸附

作     者：胡杰 李松军 刘白玲 

作者机构：中国科学院成都有机化学研究所 

出 版 物：《高分子学报》 (Acta Polymerica Sinica)

年 卷 期：2004年第14卷第5期

页      面：763-765页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 0817[工学-化学工程与技术] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

主　　题：牛血清蛋白 聚甲基丙烯酸甲酯微球 表面吸附 聚苯乙烯微球 丙烯酰胺丙磺酸 聚乙烯吡咯烷酮 过氧化苯甲酰 

摘      要：The adsorption of serum proteins on polymer microspheres is very important for their application in many *** amounts of sulfonate groups were introduced to PMMA microspheres, and the adsorption behaviors of BSA on them was studied. The apparent rate constants of various microspheres increased with the increase amount of sulfonate groups on the surface of microspheres. Adsorption isotherm curves were fitted to the Langmuir-Freundlich model. With the increase of sulfonate groups on the surface of microspheres, c-m values increased, however, K showed an opposite tendency to c-m. It is indicated that the electrostatic interaction plays a dominant role in the adsorption process, and adsorption based on electrostatic interaction is higher than that due to hydrophobic interaction, but the adsorption due to electrostatic interaction has a lower rate than that of the latter.