Liver cancer incidence and mortality in China: Temporal trends and projections to 2030

作     者：Rongshou Zheng Chunfeng Qu Siwei Zhang Hongmei Zeng Kexin Sun Xiuying Gu Changfa Xia Zhixun Yang He Li Wenqiang Wei Wanqing Chen Jie He 

作者机构：Office for Cancer RegistryNational Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Science and Peking Union Medical College State Key Laboratory of Molecular OncologyNational Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College Cancer Research InstituteAffiliated Tumor HospitalXinjiang Medical University Office of Cancer ScreeningNational Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Science and Peking Union Medical College Department of Thoracic SurgeryNational Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Science and Peking Union Medical College 

出 版 物：《Chinese Journal of Cancer Research》 (中国癌症研究（英文版）)

年 卷 期：2018年第30卷第6期

页      面：571-579页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：supported by National Natural Science Foundation of China(No.81602931) Ministry of Science and Technology(No.2014FY121100) State Key Projects Specialized on Infectious Diseases(No.2012ZX10002008) 

主　　题：Liver cancer burden temporal trends prediction cancer registry China 

摘      要：Objective: Liver cancer is one of the most common cancers and major cause of cancer deaths in China,which accounts for over 50% of new cases and deaths *** systematic liver cancer statistics including of projection through 2030 could provide valuable information for prevention and control strategies in China,and experience for other ***: The burden of liver cancer in China in 2014 was estimated using 339 cancer registries’ data selected from Chinese National Cancer Center(NCC).Incident cases of 22 cancer registries were applied for temporal trends from 2000 to *** burden of liver cancer through 2030 was projected using age-period-cohort ***: About 364,800 new cases of liver cancer(268,900 males and 95,900 females) occurred in China,and about 318,800 liver cancer deaths(233,500 males and 85,300 females) in *** regions of China had the highest incidence and mortality *** and mortality rates decreased by about 2.3% and 2.6% per year during the period of 2000-2014,respectively,and would decrease by more than 44% between 2014 and 2030 in *** young generation,particularly for those aged under 40 years,showed a faster down ***: Based on the analysis,incidence and mortality rates of liver cancer are expected to decrease through 2030,but the burden of liver cancer is still serious in China,especially in rural and western *** cases of liver cancer in China can be prevented through vaccination and more prevention efforts should be focused on high risk groups.