Effect of local longitudinal shortening on the transport of luminal contents through small intestine
作者机构:Sasi Institute of Technology and EngineeringTadepalligudem 534101India
出 版 物:《Acta Mechanica Sinica》 (力学学报(英文版))
年 卷 期:2019年第35卷第1期
页 面:45-60,I0002页
核心收录:
学科分类:08[工学] 0801[工学-力学(可授工学、理学学位)]
主 题:Circular contraction Local longitudinal shortening Lubrication theory
摘 要:A theoretical analysis of the rheological fluid flow due to peristalsis is studied. We have applied the classical lubrication theory to predict the near physiological behavior of the intestinal segment, mixing and transport. A parametric study involving the changes in local longitudinal shortening (LLS) magnitude, LLS spacing, fluid viscosity, wavelength of the wave, and occlusion of lumen caused by the wave provided insights into the dynamics of the peristalsis flow of a non-Newtonian fluid. LLS appear to have little significance in modulating the flow patterns that are caused by circular contraction alone. Results also indicate that there exists trade-off between the power requirement for peristalsis at a certain occlusion against the percentage LLS. LLS appear to be more advantageous to perform the peristalsis activity at higher occlusion than lower occlusion. Having mucosal folds in the inner lining of the intestine allows for one more advantage of slowing the transit due to increased friction factor and increase in time for absorption of the nutrients.