Sharpening emitter localization in front of a tuned mirror

作     者：Hannah S.Heil Benjamin Schreiber Ralph Götz Monika Emmerling Marie-Christine Dabauvalle Georg Krohne Sven Höfling Martin Kamp Markus Sauer Katrin G.Heinze 

作者机构：Rudolf Virchow CenterResearch Center for Experimental BiomedicineUniversity of WürzburgJosef-Schneider-Str.297080 WürzburgGermany Department of Biotechnology and BiophysicsBiozentrumUniversity of WürzburgAm Hubland97074 WürzburgGermany Technische PhysikPhysikalisches Institut and Wilhelm Conrad Röntgen-Center for Complex Material SystemsUniversity of WürzburgAm Hubland97074 WürzburgGermany Division of Electron MicroscopyBiozentrumUniversity of WürzburgAm Hubland97074 WürzburgGermany SUPASchool of Physics and AstronomyUniversity of St AndrewsSt Andrews KY169SSUK 

出 版 物：《Light(Science & Applications)》 (光（科学与应用)（英文版）)

年 卷 期：2018年第7卷第1期

页      面：71-78页

核心收录：

学科分类：080901[工学-物理电子学] 0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 080401[工学-精密仪器及机械] 0804[工学-仪器科学与技术] 0803[工学-光学工程] 

基　　金：supported by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)TRR 166 projects A04(to M.S.)and C06(to K.G.H.) the Rudolf Virchow Center of the University of Würzburg(H.S.H.) the Elite Network of Bavaria(ENB)with project K-BM-2013-247(to B.S.) the University of Würzburg(M.E.,M.K.,S.H.,and R.G.) the State of Bavaria(clean room facilities) 

主　　题：emitter mirror tunable 

摘      要：Single-molecule localization microscopy(SMLM)aims for maximized precision and a high signal-to-noise *** features can be provided by placing the emitter in front of a metal-dielectric nanocoating that acts as a tuned mirror2–***,we demonstrate that a higher photon yield at a lower background on biocompatible metal-dielectric nanocoatings substantially improves SMLM performance and increases the localization precision by up to a factor of *** resolution improvement relies solely on easy-to-fabricate nanocoatings on standard glass coverslips and is spectrally and spatially tunable by the layer design and wavelength,as experimentally demonstrated for dual-color SMLM in cells.