Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar:A single-blind observational study

作     者：Fausto Riu Pons Montserrat Andreu Javier Gimeno Beltran Marco Antonioálvarez-Gonzalez Agustín Seoane Urgorri Josep Maria Dedeu Luis Barranco Priego Xavier Bessa 

作者机构：Gastroenterology DepartmentHospital del MarBarcelona 08003Spain IMIM(Hospital del Mar Medical Research Institute)Barcelona 08003Spain Department of MedicineAutonomous University of BarcelonaBarcelona 08003Spain Pompeu Fabra UniversityBarcelona 08003Spain Pathology DepartmentHospital del MarBarcelona 08003Spain. 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2018年第24卷第45期

页      面：5179-5188页

核心收录：

学科分类：10[医学] 

主　　题：Colonoscopy Narrow band imaging Endoscopic mucosal resection 

摘      要：AIM To assess the incremental benefit of narrow band imaging(NBI) and white light endoscopy(WLE), randomizing the initial technique for the detection of residual neoplasia at the polypectomy scar after an endoscopic piecemeal mucosal resection(EPMR).METHODS We conducted an observational study in an academic center to assess the incremental benefit of NBI and WLE randomly applied 1:1(NBI-WLE or WLE-NBI) in the follow-up of a post-EPMR scar by the same *** A total of 112 EPMR scars were included. The median baseline polyp size was 20 mm(interquartile range: 14-30). At first review, NBI and WLE showed good sensitivity(85.0% vs 78.9%), specificity(77.1% vs 84.2%) and overall accuracy(80.0% vs 82.5%). NBI after WLE(WLE-NBI group) improved accuracy, but this difference was not statistically significant [area under the curve(AUC): 86.8% vs 81.6%, P = 0.15]. WLE after NBI(NBI-WLE group) did not improve accuracy(AUC: 81.4% vs 81.1%, P = 0.9). Overall, recurrence was found in 39/112(34.8%) *** Although no statistically significant differences were found between the two techniques at the first postEPMR assessment, the use of NBI after WLE may improve residual neoplasia detection. Nevertheless, biopsy is still required in the first scar review.