First Total Synthesis of 4,5-Sccoeudesmane-type and Iphionane-type Compounds-Synthesis of 4,5-Dioxo-seco-γ-eudesmol and 5β,11-Dihydroxyiphionan-4-one

作     者：Zhao Ming XIONG Gang ZHOU Xiao Lei GAO Yong Gang CHEN Yu lin LI (National Laboratory of Applied Organic Chemistry and Institute of organic Chemistry, Lanzhou University, Lanzhou 730000) 

作者机构：Natl. Lab. of Appl. Organ. Chemistry Institute of Organic Chemistry Lanzhou University Lanzhou 730000 China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2000年第11卷第2期

页      面：113-114页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the National Natural Science Foundation of China(29732060) The National Laboratory of Elemento-Organic Chemistry at Nankai University 

主　　题：type First Total Synthesis of 4,5-Sccoeudesmane-type and Iphionane-type Compounds-Synthesis of 4,5-Dioxo-seco eudesmol and 5 Dihydroxyiphionan-4-one 

摘      要：4, 5-Secoeudesmane-type and iphionane-type compounds are sesquiterpenes with new carbon skeletons found in natrual sources in recent years.1-6 The co-occurence of 4, 5-secoeudesmanes, iphionanes and eudesmanes as natrual products suggests that 4, 5-secoeudesmanes, iphionanes most likely are generated biogenetically from eudesmanes, and iphionanes are formed biogenetically by aldol reaction of 4, 5-dioxosecoeudesmanes1,4,6,7. The study on the synthesis of this two kind of new sesquiterpenes has not been reported in the literature.