Imaging of multiple myeloma: Current concepts

作     者：Thorsten Derlin Peter Bannas 

作者机构：Department of Diagnostic and Interventional RadiologyUniversity Medical Center HamburgEppendorfDE-20246 HamburgGermany 

出 版 物：《World Journal of Orthopedics》 (世界骨科杂志（英文版）)

年 卷 期：2014年第5卷第3期

页      面：272-282页

学科分类：0403[教育学-体育学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100214[医学-肿瘤学] 100106[医学-放射医学] 10[医学] 

主　　题：Multiple myeloma Plasmocytoma X-Ray Magnetic resonance imaging Diffusion-weighted imaging Positron emission tomography-computed tomography Imaging 

摘      要：Medical imaging is of crucial importance for diagnosis and initial staging as well as for differentiation of multiple myeloma(MM)from other monoclonal plasma cell *** radiography represents the reference standard for diagnosis of MM due to its wide availability and low costs despite its known limitations such as low sensitivity,limited specificity and its inability to detect extraosseous *** conventional radiography,newer cross-sectional imaging modalities such as whole-body low-dose computed tomography(CT),whole-body magnetic resonance imaging(MRI)and18F-fluorodeoxyglucose(FDG)positron emission tomography(PET)/CT are available for the diagnosis of osseous and extraosseous manifestations of ***-body low-dose CT is used increasingly,replacing conventional radiography at selected centers,due to its higher sensitivity for the detection of osseous lesions and its ability to diagnose extraosseous *** highest sensitivity for both detection of bone marrow disease and extraosseous lesions can be achieved with whole-body MRI and18F-FDG PET/*** to current evidence,MRI is the most sensitive method for initial staging while18F-FDG PET/CT allows monitoring of treatment of *** is an evolving role for assessment of treatment response using newer MR *** studies are needed to further define the exact role of the different imaging modalities for individual risk stratification and therapy monitoring.