Extensive multiarterial resection attending total duodenopancreatectomy and adrenalectomy for MEN-1-associated neuroendocrine carcinomas

作     者：Vyacheslav Ivanovich Egorov Alexander Felixovich Kharazov Alla Ivanovna Pavlovskaya Roman Valeryevich Petrov Natalia Sergeevna Starostina Eugeny Valerievich Kondratiev Ekaterina Mikhailovna Filippova 

作者机构：Department of Hepatopancreatobiliary SurgeryVishnevsky Institute of Surgery117997 MoscowRussia Department of Vascular SurgeryVishnevsky Institute of Surgery117997 MoscowRussia Department of PathologyBlokhin Cancer Research Centre Moscow117997 MoscowRussia Department of RadiologyVishnevsky Institute of Surgery117997 MoscowRussia Department of PathologyVishnevsky Institute of Surgery117997 MoscowRussia 

出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)

年 卷 期：2012年第4卷第10期

页      面：238-245页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Miratorg(R) company 

主　　题：Total duodenopancreatectomy Pancreatic neuroendocrine tumors Islet cell tumors Neuroendocrine carcinoma Multiple endocrine neoplasia type 1 syndrome 

摘      要：Pancreatic neuroendocrine tumors(PNTs) are relatively uncommon although these neoplasms have been noted to grow in occurrence in recent *** removal of locally advanced PNTs involving major vessels and adjacent organs is warranted by reason of an appreciably more favorable prognosis as compared to exocrine pancreas *** are reporting a case of successful multi-organ resection combined with a wide excision of the superior mesenteric,common,proper,left and right hepatic arteries(in the presence of the hepatomesenteric trunk variant of aberrant arterial anatomy) for multifocal PNTs in the setting of multiple neuroendocrine neoplasia type 1 *** procedure resulted in pain abolition,a significant improvement in the patient s life quality and allowed her to return to ***-up computed tomography at 15 mo post-surgery showed no evidence of disease recurrence.