Radiofrequency ablation of locally advanced pancreatic adenocarcinoma:An overview

作     者：Mirko D’Onofrio Emilio Barbi Roberto Girelli Enrico Martone Anna Gallotti Roberto Salvia Paolo Tinazzi Martini Claudio Bassi Paolo Pederzoli Roberto Pozzi Mucelli 

作者机构：Department of RadiologyUniversity Hospital G.B.RossiUniversity of Verona Department of RadiologyHospital"Casa di Cura Pederzoli"-Peschiera Department of SurgeryHospital"Casa di Cura Pederzoli"-Peschiera Department of SurgeryUniversity Hospital G.B.RossiUniversity of Verona 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2010年第16卷第28期

页      面：3478-3483页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Radiofrequency ablation Pancreatic adenocarcinoma Intraoperative ultrasound Contrast-enhanced ultrasound Perfusion computed tomography 

摘      要：Radiofrequency ablation(RFA)of pancreatic neoplasms is restricted to locally advanced,non-resectable but nonmetastatic tumors.RFA of pancreatic tumors is nowadays an ultrasound-guided procedure performed during laparotomy in open surgery.Intraoperative ultrasound covers the mandatory role of staging,evaluation of feasibility,guidance and monitoring of the procedure.Different types of needle can be used.The first aim in the evaluation of RFA as a treatment for locally advanced pancreatic ductal adenocarcinoma,in order of evaluation but not of importance,is to determine the feasibility of the procedure.The second aim is to establish the effect of RFA on tumoral mass in terms of necrosis andcytoreduction.The most important aim,third in order of evaluation,is the potential improvement of quality of life and survival rate.Nowadays,only a few studies assess the feasibility of the procedure.The present paper is an overview of RFA for pancreatic adenocarcinoma.