Peritoneal carcinomatosis from advanced ovarian cancer: To treat or not to treat ethical issues suggested by a case study

作     者：Mirco Nacoti Elena Colombetti Maria Simonetta Spada Marco Ceresoli Luca Ansaloni Gianmariano Marchesi Luca Lorini Davide Corbella Federico Coccolini 

作者机构：Anesthesia and Intensive Care Department Papa Giovanni XXIII Hospital 24127 Bergamo Italy Centre for Bioethics Università Cattolica del Sacro Cuore di Milano 20121 Milan Italy Clinical Psychology Unit Papa Giovanni XXIII Hospital 24127 Bergamo Italy General Surgery Departement Papa Giovanni XXIII Hospital 24127 Bergamo Italy 

出 版 物：《World Journal of Obstetrics and Gynecology》 (世界妇产科杂志)

年 卷 期：2014年第3卷第1期

页      面：14-20页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Advanced epithelial ovarian cancer Perito-neal carcinomatosis Platform World Health Organiza-tion-International Classifcation of Functioning Disability and health Ethical issues Hyperthemic intraperitoneal chemotherapy Health related quality of life 

摘      要：This article provides a brief description of an epithelial ovarian cancer （EOC） case （stage Ⅳ） treated with the association of complete CytoReductive Surgery and hy-pertermic intraPEritoneal chemotherapy （HIPEC）. The use of HIPEC in EOC makes theoretic sense in view of the high rates of recurrence following standard treat-ment, but there are no randomized clinical trial to date and HIPEC for these patients still represents a radical treatment where the choice of no treatment may be acceptable since defnitive cure is unlikely. We reviewed the entire decision making process considering the risk/beneft of the procedure in term of mortality/morbidity, the quality of life and the psychological profile of the patient 1 year after surgery. The platform World Health Organization-International Classification of Function-ing, Disability and Health that permits evaluation of the person in relation to the psycho-social context is pre-sented. A person-centred approach and assessment of health-related quality-of-life and disability in EOC survi-vors are of central importance for decision making.