IgE regulates airway smooth muscle phenotype:Future perspectives in allergic asthma

作     者：Naresh Singh Redhu Abdelilah S Gounni 

作者机构：Division of GI/NutritionBoston Children's Hospital Harvard Medical School Department of Immunology Faculty of Health Sciences College of Medicine University of Manitoba 

出 版 物：《World Journal of Immunology》 (世界免疫学杂志)

年 卷 期：2016年第6卷第3期

页      面：126-130页

学科分类：12[管理学] 1204[管理学-公共管理] 120402[管理学-社会医学与卫生事业管理(可授管理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 10[医学] 

主　　题：IgE Airway Allergic asthma Remodeling Inflammation 

摘      要：The purpose of this commentary is to highlight the emerging role of IgE on airway smooth muscle(ASM) cells function through activation of the high-affinity Fc receptor for IgE. We discuss the potential implications of IgE-mediated ASM sensitization in airway inflammation and remodeling, the hallmark features of allergic asthma.