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A specific and selective chemiluminescent probe for Pd^(2+) detection

A specific and selective chemiluminescent probe for Pd^(2+) detection

作     者:Yuqi Gao Yuxing Lin Tingting Liu Xiaomeng Zhang Feng Xu Pan Liu Lupei Du Minyong Li 

作者机构:Department of Medicinal Chemistry Key Laboratory of Chemical Biology (MOE) School of Pharmacy Shandong University State Key Laboratory of Microbial Technology Shandong University 

出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))

年 卷 期:2019年第30卷第1期

页      面:63-66页

核心收录:

学科分类:07[理学] 0703[理学-化学] 

基  金:supported by grants from the Taishan Scholar Program at Shandong Province,the Qilu/Tang Scholar Program at Shandong University the Key Research and Development Project of Shandong Province (No. 2017CXGC1401) the Major Project of Science and Technology of Shandong Province (No. 2015ZDJS04001) 

主  题:Chemiluminescent imaging Chemiluminescence 1,2-Dioxetane Palladium(Ⅱ) Bioassays 

摘      要:As an important transition metal catalyst, palladium is extensively used in many areas including electronics industry, petroleum industry, automobile industry and fine chemicals engineering. However,it brings harm to the environment as well as people s health. Herein, we managed to introduce a butynyl group to 1,2-dioxetane developing a reaction-based chemiluminescent probe as well as an imaging approach for monitoring palladium(II). Exhibiting enhanced total flux in Pd2+enriched areas, palladium chemiluminescent probe(PCL) may afford potential utility for detecting Pd2+in vitro, in cellulo and in vivo.

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