Applications of scanning femtosecond laser-induced ionization microscopy in biological imaging

作     者：Youbo ZHAO Yanmei LIANG Xiaonong ZHU 

作者机构：Institute of Modern Optics Nankai University Key Laboratory of Opto-electronic Information Science and Technology Ministry of Education of China 

出 版 物：《Frontiers of Optoelectronics》 (光电子前沿(英文))

年 卷 期：2008年第1卷第Z2期

页      面：201-204页

学科分类：080901[工学-物理电子学] 0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 080401[工学-精密仪器及机械] 0804[工学-仪器科学与技术] 0803[工学-光学工程] 

基　　金：supported by the State Key Program of National Natural Science Foundation of China (Grant No. 60637020) 

主　　题：nonlinear microscopy laser-tissue interaction ultrafast laser bio-imaging 

摘      要：The applicability and potential advantages of femtosecond laser-induced ionization microscopy in examining biological samples are demonstrated. Highresolution section images of the inner structures and the topographical surface profiles of a piece of unstained onion skin and a human oral epithelium specimen are obtained by collecting the plasma emission signals generated either inside the samples or from air in the vicinity. It is concluded that the high material discrimination capability and the minimum damage effect give this laser-induced ionization imaging technique great potentials in the area of biological imaging and medical analyses.