Mass transfer mechanisms in fixed-bed adsorption of erythromycin
在抗生素的一种的改正床吸附的传质机制作者机构：Chemical Engineering Research CentreEast China University of Science and TechnologyShanghai 200237China
出 版 物：《Frontiers of Chemical Science and Engineering》 (化学科学与工程前沿（英文版）)
年 卷 期：2008年第2卷第4期
页 面：353-360页
核心收录：
学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学]
主 题：fixed-bed adsorption superficial velocity ionic strength erythromycin However investigations on the parameters governing the performance of this technology are still scarce.In the present work a polymeric and porous resin Sepabeads SP825 resin was used for its higher adsorption efficiency compared with the resins reported.The equilib-rium capacity of Sepabeads SP825 for EM in a batch system was established using a Langmuir isotherm.The effects of superficial velocity ionic strength and pH on the adsorption process were determined from the results of fixed bed experiments.And a model of the purification process was used to simulate the mass transfer mechanism which has taken film mass transfer pore diffusion and axial dispersion into account.The experimental adsorp-tion measurements were compared to the results calcu-lated from the model.The completion of these studies provide some essential parameters which are required in order to design a successful purification process and better understand the fundamentals of these process.
摘 要：The equilibrium and kinetic characteristics of the adsorption of erythromycin to Sepabeads SP825 were *** equilibrium data in a batch system was well described by a Langmuir *** separation performance was investigated in a fixed-bed system with respect to the adsorption superficial velocity,ionic strength and pH.A mathematical model was used to simulate the mass transfer mechanism,taking film mass transfer,pore diffusion and axial dispersion into *** model predictions were consistent with the experi-mental data and were consequently used to determine the mass transfer coefficients.
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