What is new in central serous chorioretinopathy?
What is new in central serous chorioretinopathy?作者机构：Department of Ophthalmology Rabin Medical CenterPetach Tikva 49100 Israel
出 版 物：《World Journal of Ophthalmology》 (世界眼科杂志)
年 卷 期：2014年第4卷第4期
页 面：113-123页
学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
主 题：Central serous chorioretinopathy Optical coherence tomography Fundus autoflouresence Multifocal electroretinography Macular microperimetry
摘 要：Central serous chorioretinopathy(CSCR) is considered a benign, self-limiting disease. However, as many as third of the patients have recurrent episodes or chronic disease that may cause significant functional impairment. New diagnostic tools and new treatment modalities are emerging in order to improve the functional outcomes of these patients. Spectral domain optical coherence tomography(SD-OCT) has the ability to image individual layers of the retina and choroid. SD-OCT images in CSCR patients have demonstrated increased subfoveal thickness measurements, high reflective deposits in areas of subretinal precipitates and changes in the Retinal pigment epithelium layers of the asymptomatic eyes of patients with supposedly unilateral CSCR. A positive correlation was found between the level of distribution to the layer of inner segment/outer segment junction of the photoreceptors and the visual impairment. Fundus autoflouresence images show a wide variety during different stages of the disease in CSCR patients. Minimal abnormalities during the early stages are followed by hyperautofluoresence in the detached area in later stages, often in a manner of inferior gravitation and at the borders of the detachments. The chronic phase is characterized by varying degrees of atrophy and areas of decreased autofluorescence surrounding areas ofchronic leaks. These changes help differentiate an active disease from an inactive state. Multifocal electroretinography(mf ERG) has the ability to demonstrate a persistent depression despite the resolution of subretinal detachments. It is therefore being investigated as a follow up tool for patients with chronic CSCR. An excellent correlation was found between changes in mf ERG and visual function. Macular microperimetry, measuring retinal sensitivity within the central visual field, is intended to compensate for the underestimation of visual impairment in patients with macular diseases. Reduced retinal sensitivity was found in areas of prev
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