Transcranial direct current stimulation in psychiatric disorders

作     者：Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni 

作者机构：Service of Interdisciplinary NeuromodulationLaboratory of Neurosciences (LIM-27)Department and Institute of PsychiatryUniversity of Sao Paulo Interdisciplinary Center for Applied NeuromodulationUniversity HospitalUniversity of Sao Paulo Psychology DepartmentAdvanced School in NeuropsychologyUniversità degli Studi Milano Bicocca Department of PhysiologyPharmacology and Neuroscience Sophie Davis School of Biomedical Education City University of New York (CUNY) Obsessive Compulsive Disorder Project (PROTOC)Department and Institute of PsychiatryUniversity of Sao Paulo Unit of Psychiatry Department of NeurosciencesReproductive and Odontostomatological Sciences University of Naples Federico II Université de Lyon Université Claude Bernard Lyon ICentre Hospitalier le Vinatier National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq)Department of Psychiatry Department and Institute of PsychiatryUniversity of Sao Paulo Santa Casa de Sao Paulo Medical School Institute of Physical Medicine and RehabilitationClinics Hospital of the University of Sao Paulo Medical School 

出 版 物：《World Journal of Psychiatry》 (世界精神病学杂志)

年 卷 期：2015年第5卷第1期

页      面：88-102页

学科分类：1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学] 

主　　题：Non-invasive brain stimulation Transcranial direct current stimulation Psychiatry disorders Review 

摘      要：The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry.