Effect of early surgery in high surgical risk geriatric patients with femoral neck fracture and taking antiplatelet agents

作     者：Paphon Sa-ngasoongsong Noratep Kulachote Norachart Sirisreetreerux Pongsthorn Chanplakorn Sukij Laohajaroensombat Nithiwut Pinsiranon Patarawan Woratanarat Viroj Kawinwonggowit Chanyut Suphachatwong Wiwat Wajanavisit 

作者机构：Department of OrthopedicsFaculty of Medicine Ramathibodi HospitalMahidol University 

出 版 物：《World Journal of Orthopedics》 (世界骨科杂志（英文版）)

年 卷 期：2015年第6卷第11期

页      面：970-976页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Early hip surgery Blood loss Elderly hip fracture Antiplatelet agents Displaced femoral neck fracture Hip arthroplasty 

摘      要：AIM: To investigate the effect of early surgical intervention on the high surgical risk elderly patients who sustained femoral neck fracture(FNF) and taking concomitant antiplatelet agents. METHODS: Between 2010 and 2012, a prospective study was conducted on 49 geriatric patients, who took antiplatelet agents, sustained FNF and underwent surgery within 72 h [early surgery(ES) group], and these were compared with a retrospective consecutive case series of patients with similar characteristics(45 cases) who had delayed surgery(DS group) after 72 h during an earlier 3-year period. Postoperative outcomeswere followed for one year and compared. RESULTS: There were non-significant differences in perioperative blood loss, blood transfusion, intensive care unit requirement and postoperative mortality(P 0.05 all). There were 2 patients(4%) in the DS group who died after surgery(P = 0.23). However, the ES group showed a significantly better postoperative outcome in terms of postoperative complications, length of hospital stay, and functional outcome(P 0.05 all).CONCLUSION: Early hip surgery in geriatric hip fracture patients with ongoing antiplatelet treatment was not associated with a significant increase of perioperative blood loss and postoperative mortality. Moreover, ES resulted in a better postoperative surgical outcome. In early hip surgery protocol, the antiplatelet agents are discontinued and the patient is operated on within 72 h after admission, which is safe and effective for the medically fit patients.