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Challenges and opportunities in the treatment of ulcerative colitis

Challenges and opportunities in the treatment of ulcerative colitis

作     者:Sunil Ashokrao Nirmal Sunil Shivaji Gangurde Pratiksha Shankar Dumbre Subodh Chandra Pal Subhash Chandra Mandal 

作者机构:Department of PharmacognosyPravara Rural College of Pharmacy Biotechnology CentrePost Graduate InstituteDr. PDKVMaharashtra 413736India Sarswati Vidyabhavan College of Pharmacy Department of PharmacognosyNDMVP’s College of Pharmacy Pharmacognosy and Phytotherapy Research LaboratoryDivision of PharmacognosyDepartment of Pharmaceutical TechnologyJadavpur University 

出 版 物:《World Journal of Pharmacology》 (世界药理学杂志)

年 卷 期:2015年第4卷第2期

页      面:219-226页

学科分类:100506[医学-中医内科学] 1006[医学-中西医结合] 1005[医学-中医学] 1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 100602[医学-中西医结合临床] 

主  题:溃疡性结肠炎 直肠 治疗方法 临床分析 

摘      要:Ulcerative colitis(UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and lower part of the colon as well as the entire colon. Drug therapy is not the only choice for UC treatment and medical management should be as a comprehensive whole. Many synthetic drugs are available for the treatment of UC like 5-aminosalicylic acid, oral or systemic corticosteroids, immunomodulator, etc. but these drugs are associated with many serious side effects after long term use or have certain disadvantage or not suitable for the use in some patients. In short synthetic drugs have many disadvantages and for this reason effective and safe alternative drug treatment for the UC is the challenge. Herbal drugs are found to be very promising results of the treatment of UC and enzymatic level. Researchers explored many herbal drugs for the treatment and even many more may found effective in the treatment of UC. At this point we feel herbal medicine is the better alternative for the treatment of UC.

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