Relationship between biological factors and catastrophizing and clinical outcomes for female patients with knee osteoarthritis

作     者：Tatsunori Ikemoto Hirofumi Miyagawa Yukiko Shiro Young-Chang Park Arai Machiko Akao Kenta Murotani Takahiro Ushida Masataka Deie 

作者机构：Institute of Physical Fitness Sports Medicine and Rehabilitation Aichi Medical University Department of Physical Therapy Faculty of Rehabilitation Sciences Nagoya Gakuin University Department of Orthopedic Surgery Aichi Medical University Division of Biostatistics Clinical Research Center Aichi Medical University 

出 版 物：《World Journal of Orthopedics》 (世界骨科杂志（英文版）)

年 卷 期：2017年第8卷第3期

页      面：278-285页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Osteoarthritis Pain catastrophizing Knee pain Physical function Japanese Knee Osteoarthritis Measure 

摘      要：AIM To investigate the correlations between clinical outcomes and biopsychological variables in female patients with knee osteoarthritis(OA).METHODS Seventy-seven patients with symptomatic knee OA were enrolled in this *** investigated the age,body mass index(BMI),pain catastrophizing scale(PCS)and radiographic severity of bilateral knees using a Kellgren-Lawrence(K-L)grading system of the ***,a multiple linear regression was conducted to determine which variables best correlated with main outcomes of knee OA,which were pain severity,moving capacity by measuring timed-up-and-go test and Japanese Knee Osteoarthritis Measure(JKOM).RESULTS We found that the significant contributor to pain severity was PCS(β=0.555)and BMI(β=0.239),to moving capacity was K-L grade(β=0.520)and to PCS(β=0.313),and to a JKOM score was PCS(β=0.485)and K-L grade(β=0.421),*** The results suggest that pain catastrophizing as well as biological factors were associated with clinical outcomes in female patients with knee OA,irrespective of radiographic severity.