Epidemiology, pathophysiology, clinical characteristics and management of childhood cardiorenal syndrome

作     者：Wasiu A Olowu 

作者机构：Paediatric Nephrology and Hypertension UnitObafemi Awolowo University Teaching Hospitals Complex IleIfe Osun State 234 Nigeria Department of Paediatrics and Child HealthFaculty of Clinical Sciences Obafemi Awolowo University IleIfe Osun State 234 Nigeria 

出 版 物：《World Journal of Nephrology》 (世界肾病学杂志（英文版）)

年 卷 期：2012年第1卷第1期

页      面：16-24页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Acute kidney injury Congestive heart failure Chronic kidney disease Ultrafltration 

摘      要：Cardiorenal syndrome(CRS) is a new term recently introduced to describe the acute or chronic comorbid state of the heart and kidney that has been long known and frequently managed in very sick individuals. The tight and delicate coordination of physiological functions among organ systems in the human body makes dysfunction in one to lead to malfunction of one or more other organ systems. CRS is a universal very common morbidity in the critically ill, with a high mortality rate that has received very little research attention in children. Simultaneous management of heart and renal failures in CRS is quite challenging; the therapeutic choice made for one organ must not jeopardize the other. This paper reviews the epidemiology, pathophysiology, clinical characteristics and management of acute and chronic CRS in children.