Sentinel lymph node biopsy in renal malignancy: The past, present and future
Sentinel lymph node biopsy in renal malignancy: The past, present and future作者机构：Department of Urology St George’s Hospital
出 版 物：《World Journal of Nephrology》 (世界肾病学杂志（英文版）)
年 卷 期：2016年第5卷第2期
页 面：182-188页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Sentinel lymph node biopsy Dynamic sentinel node Renal malignancy Lymphoscintigraphy Near infra-red fuorescence Penile cancer Lymphatic drainage
摘 要：Sentinel lymph node biopsy （SLNB） is now an establishedtechnique in penile and pelvic cancers, resulting in alower mortality and morbidity when compared withthe traditional lymph node dissection. In renal cancer however, despite some early successes for the SLNB technique, paucity of data remains a problem, thus lymph node dissection and extended lymph node dissection remain the management of choice in clinically node positive patients, with surveillance of lymph nodes in those who are clinically node negative. SLNB is a rapidly evolving technique and the introduction of new techniques such as near infra-red fuorescence optical imaging agents and positron emission tomography/computed tomography scans, may improve sensitivity. Evidence in support of this has already been recorded in bladder and prostate *** the lack of large multi-centre studies and issues around false negativity currently prevent its widespread use, with evolving techniques improving accuracy and the support of large-scale studies, SLNB does have the potential to become an integral part of staging in renal malignancy.
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