The potential of small molecule brain-derived neurotrophic factor: mimetics to treat inherited retinal degeneration

作     者：Andrea Cerquone Perpetuini Justine Mathoux Breandán N.Kennedy 

作者机构：School of Biomolecular & Biomedical Science Conway Institute University College Dublin 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2019年第14卷第1期

页      面：85-86页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基　　金：received funding from the Science Foundation Ireland/Enterprise Ireland(SFI/EI)Technology Innovation Development Award(TIDA)grant No.17/TIDA/4993 the European Union’s Horizon 2020 research and innovation programme under grant agreement No.734907(RISE/3D-NEONET project) 

主　　题：小分子 神经营养 退化 大脑 膜 基因 植入 生物 

摘      要：Is there a need for small molecule neuroprotectants in inherited retinal degeneration(iRDs)?iRDs are a heterogeneous cluster of diseases which lead to blindness in 1 in every 2–3000 people.A plethora of causative genetic defects were revealed in the last *** research focuses on development of pharmacological,biological or mechanical implant ***