Polymorphisms of MTHFR and susceptibility to oesophageal adenocarcinoma in a Caucasian United Kingdom population

作     者：Richard Keld Manyi Thian Chia Hau Jamil Sajid Narveen Kumar Yeng Ang 

作者机构：Department of GastroenterologyRoyal Albert Edward InfirmaryWiganLancashire WN1 2NNUnited Kingdom Faculty of Human and Medical SciencesUniversity of ManchesterManchesterSalford M6 8HDUnited Kingdom 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第34期

页      面：12212-12216页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported by Endowment funds of the Wrightington,Wigan and Leigh NHS Foundation Trust Ang Y received support from Comprehensive Local Research Network of Greater Manchester and Cheshire,United Kingdom(flexibility and sustainability grant) 

主　　题：Polymorphisms of 5,10-methylenetetrahydrofolate reductase Oesophageal adenocarcinoma Caucasian population Helicobacter pylori Polymorphism 

摘      要：AIM: To identify if methylene tetra-hydrofolatereductase (MTHFR) C677T polymorphisms are associated with oesophageal adenocarcnomas in a Caucasian population and to test whether folic acid and homocysteine levels are linked with cancer risk.