VERTICAL HEREDITY VS. HORIZONTAL GENE TRANSFER: A CHALLENGE TO BACTERIAL CLASSIFICATION

作     者：HAO Bailin(Institute of Theoretical Physics, Academy of Chinese Sciences, Beijing 100080, China Senior International Fellow of the Santa Fe Institute T-Life Research Center, Fudan University,Shanghai 200433, China)QI Ji(Institute of Theoretical Physics, Beijing 100080, China) 

作者机构：Institute of Theoretical Physics Academy of Chinese Sciences 北京 100080 Institute of Theoretical Physics Chinese Academy of Sciences 北京 100080 

出 版 物：《Journal of Systems Science & Complexity》 (系统科学与复杂性学报（英文版）)

年 卷 期：2003年第16卷第3期

页      面：307-314页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071007[理学-遗传学] 

基　　金：This work was partially supported by the Natural Science Foundation of China the Special Funds for Major State Basic Research Project the Innovation Project of the Chinese Academy of Sciences and the Major Innovation Research Project"248"of Beijing Munic 

主　　题：prokaryote phylogeny horizontal gene transfer fitness compositionaldistance 

摘      要：The diversity and classification of microbes has been a long-standing *** phylogeny of the prokaryotes based on comparison of the 16S rRNA sequences of the small ribosomal subunit has led to a reasonable tree of life in the late 1970s. How-ever, the availability of more and more complete bacterial genomes has brought about complications instead of refinement of the tree. In particular, it turns out that different choice of genes may tell different history. This might be caused by possible horizontal gene transfer (HGT) among species. There is an urgent need to develop phylogenetic methods that make use of whole genome data. We describe a new approach in molecular phylogeny,namely, tree construction based on K-tuple frequency analysis of the genomic *** aside the technicalities, we emphasize the transition from randomness to determin-ism when the string length K increases and try to comment on the challenge mentioned in the title.