Theory,simulations and the design of functionalized nanoparticles for biomedical applications:A Soft Matter Perspective

作     者：Stefano Angioletti-Uberti 

作者机构：Department of MaterialsImperial College LondonLondon SW72AZUK Beijing Advanced Innovation Centre for Soft Matter Science and EngineeringBeijing University of Chemical Technology100099 BeijingPR China 

出 版 物：《npj Computational Materials》 (计算材料学（英文）)

年 卷 期：2017年第3卷第1期

页      面：52-66页

核心收录：

学科分类：08[工学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

基　　金：Beijing Advanced Innovation Centre for Soft Matter Science and Engineering Alexander von Humboldt-Stiftung European Research Council, ERC 

主　　题：functional meaningful biomedical 

摘      要：Functionalised nanoparticles for biomedical applications represents an incredibly exciting and rapidly growing field of *** the complexity of the nano-bio interface,an important question is to what extent can theory and simulations be used to study these systems in a realistic,meaningful *** this review,we will argue for a positive answer to this *** the issue from a“Soft Matterperspective,we will consider those properties of functionalised nanoparticles that can be captured within a classical *** will thus not concentrate on optical and electronic properties,but rather on the way nanoparticles’interactions with the biological environment can be tuned by functionalising their surface and exploited in different contexts relevant to *** particular,we wish to provide a critical overview of theoretical and computational coarsegrained models,developed to describe these interactions and present to the readers some of the latest results in this fascinating area of research.